{"id":87,"date":"2015-05-04T15:32:18","date_gmt":"2015-05-04T15:32:18","guid":{"rendered":"http:\/\/bme.ufl.edu\/labs\/stabler\/?page_id=87"},"modified":"2025-11-20T15:41:37","modified_gmt":"2025-11-20T19:41:37","slug":"engineering-site-for-islet-transplantation","status":"publish","type":"page","link":"https:\/\/faculty.eng.ufl.edu\/stabler\/research\/engineering-site-for-islet-transplantation\/","title":{"rendered":"Engineering Site for Islet Transplantation"},"content":{"rendered":"<div class=\"wp-block-image\">\n<figure class=\"alignright size-large is-resized\"><img loading=\"lazy\" decoding=\"async\" width=\"680\" height=\"1024\" src=\"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-content\/uploads\/sites\/497\/2015\/05\/DRI_Day-Two_hi-res_047-low-680x1024.jpg\" alt=\"\" class=\"wp-image-53\" style=\"width:250px\" srcset=\"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-content\/uploads\/sites\/497\/2015\/05\/DRI_Day-Two_hi-res_047-low-680x1024.jpg 680w, https:\/\/faculty.eng.ufl.edu\/stabler\/wp-content\/uploads\/sites\/497\/2015\/05\/DRI_Day-Two_hi-res_047-low-199x300.jpg 199w, https:\/\/faculty.eng.ufl.edu\/stabler\/wp-content\/uploads\/sites\/497\/2015\/05\/DRI_Day-Two_hi-res_047-low-768x1156.jpg 768w, https:\/\/faculty.eng.ufl.edu\/stabler\/wp-content\/uploads\/sites\/497\/2015\/05\/DRI_Day-Two_hi-res_047-low-1021x1536.jpg 1021w, https:\/\/faculty.eng.ufl.edu\/stabler\/wp-content\/uploads\/sites\/497\/2015\/05\/DRI_Day-Two_hi-res_047-low-1361x2048.jpg 1361w, https:\/\/faculty.eng.ufl.edu\/stabler\/wp-content\/uploads\/sites\/497\/2015\/05\/DRI_Day-Two_hi-res_047-low-scaled.jpg 1701w\" sizes=\"auto, (max-width: 680px) 100vw, 680px\" \/><\/figure>\n<\/div>\n\n\n<p>Engineering of ideal transplant sites for cell transplantation through the use of bioactive materials is a major focus of our laboratory, specifically the combination of biomaterials and active agents to generate a favorable site for islet or beta cell transplantation. Engineered biomaterial scaffolds, like the one shown above, can create optimal sites for housing islets. With a focus on enhancing oxygenation and vascularization, as well as local immunomodulation, to the engraftment site of islets, we have developed several platform technologies:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><span style=\"text-decoration: underline\"><a href=\"https:\/\/faculty.eng.ufl.edu\/stabler\/research\/engineering-site-for-islet-transplantation\/macro-porous-scaffolds\/\" data-type=\"link\" data-id=\"https:\/\/faculty.eng.ufl.edu\/stabler\/research\/engineering-site-for-islet-transplantation\/macro-porous-scaffolds\/\">Macro-porous scaffolds<\/a><\/span><\/li>\n\n\n\n<li><span style=\"text-decoration: underline\"><a href=\"https:\/\/faculty.eng.ufl.edu\/stabler\/research\/engineering-site-for-islet-transplantation\/oxysite-oxygen-generating-biomaterial\/\" data-type=\"link\" data-id=\"https:\/\/faculty.eng.ufl.edu\/stabler\/research\/engineering-site-for-islet-transplantation\/oxysite-oxygen-generating-biomaterial\/\">OxySite \u2013 Oxygen Generating Biomaterial<\/a><\/span><\/li>\n\n\n\n<li><span style=\"text-decoration: underline\"><a href=\"https:\/\/faculty.eng.ufl.edu\/stabler\/research\/engineering-site-for-islet-transplantation\/immunomodulatory-biomaterials\/\" data-type=\"link\" data-id=\"https:\/\/faculty.eng.ufl.edu\/stabler\/research\/engineering-site-for-islet-transplantation\/immunomodulatory-biomaterials\/\">Immunomodulatory Biomaterials<\/a><\/span><\/li>\n<\/ol>\n\n\n\n<p><\/p>\n\n\n\n<h6 class=\"wp-block-heading has-text-align-center\"><br>Efforts in this area are currently being supported by the <a href=\"http:\/\/jdrf.org\/\">JDRF <\/a>and <a href=\"https:\/\/projectreporter.nih.gov\/project_info_description.cfm?aid=10142609&amp;icde=53151316&amp;ddparam=&amp;ddvalue=&amp;ddsub=&amp;cr=3&amp;csb=default&amp;cs=ASC&amp;pball=\">NIH<\/a><\/h6>\n\n\n\n<div style=\"height:1px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div style=\"height:10px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Engineering of ideal transplant sites for cell transplantation through the use of bioactive materials is a major focus of our laboratory, specifically the combination of biomaterials and active agents to generate a favorable site for islet or beta cell transplantation. Engineered biomaterial scaffolds, like the one shown above, can create optimal sites for housing islets. [&hellip;]<\/p>\n","protected":false},"author":468,"featured_media":0,"parent":84,"menu_order":5,"comment_status":"closed","ping_status":"closed","template":"page-templates\/page-section-nav.php","meta":{"_acf_changed":false,"inline_featured_image":false,"featured_post":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-87","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/pages\/87","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/users\/468"}],"replies":[{"embeddable":true,"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/comments?post=87"}],"version-history":[{"count":15,"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/pages\/87\/revisions"}],"predecessor-version":[{"id":5083,"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/pages\/87\/revisions\/5083"}],"up":[{"embeddable":true,"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/pages\/84"}],"wp:attachment":[{"href":"https:\/\/faculty.eng.ufl.edu\/stabler\/wp-json\/wp\/v2\/media?parent=87"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}