{"id":27,"date":"2025-05-05T20:11:37","date_gmt":"2025-05-05T20:11:37","guid":{"rendered":"https:\/\/oweisslab.ece.ufl.edu\/?page_id=27"},"modified":"2025-05-05T20:11:37","modified_gmt":"2025-05-05T20:11:37","slug":"about","status":"publish","type":"page","link":"https:\/\/faculty.eng.ufl.edu\/oweisslab\/about\/","title":{"rendered":"About"},"content":{"rendered":"\n<p><\/p>\n\n\n\n<figure class=\"wp-block-pullquote has-medium-font-size\"><blockquote><p>\u201cThere is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.\u201d<\/p><cite>Francis crik<\/cite><\/blockquote><\/figure>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p><\/p>\n<\/blockquote>\n<\/blockquote>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:28% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"998\" height=\"1024\" src=\"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/Neurons-1-998x1024.png\" alt=\"\" class=\"wp-image-277 size-full\" srcset=\"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/Neurons-1-998x1024.png 998w, https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/Neurons-1-293x300.png 293w, https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/Neurons-1-768x788.png 768w, https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/Neurons-1.png 1445w\" sizes=\"auto, (max-width: 998px) 100vw, 998px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"has-text-align-center has-white-color has-dark-gray-background-color has-text-color has-background has-link-color has-x-large-font-size wp-elements-f25f1adec335b1a7d9a6ac5bbdcc3082\">Basic Neuroscience<\/p>\n<\/div><\/div>\n\n\n\n<p>My lab has a long-standing interest in investigating the neural mechanisms underlying sensorimotor integration, and the extent to which they can guide the engineering of clinically viable Brain machine Interfaces (BMIs). In particular, we seek to characterize the interaction between cortical and subcortical structures at the cellular and population levels during goal-directed behavior. Some sample publications:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>I-Wen Chen, Chung Yuen Chan, Phillip Navarro. Vincent de Sars, Emiliano Ronzitti, Karim Oweiss, Dimitrii Tanese, Valentina Emiliani (2025) &#8220;High-throughput synaptic connectivity mapping using in vivo two-photon holographic optogenetics and compressive sensing&#8221; Nature Neuroscience, doi: 10.1038\/s41593-025-02024-y<\/li>\n\n\n\n<li>S. Eldawlatly, K. Oweiss, (2014) \u201cTemporal precision in population &#8211; but not individual neuron &#8211; dynamics reveals rapid experience-dependent plasticity in the rat barrel cortex\u201d Frontiers in Computational Neuroscience, Vol 8, doi: 10.3389\/fncom.2014.00155<\/li>\n\n\n\n<li>S. Eldawlatly, K. Oweiss (2011) \u201cMillisecond-Timescale Local Network Coding in the Rat Primary Somatosensory Cortex,\u201d PLoS ONE 6(6): e21649. PMID: 21738751<\/li>\n\n\n\n<li>M. Aghagolzadeh, S. Eldawlatly and K. Oweiss, (2010) \u201cSynergistic Coding by Cortical Neural Ensembles\u201d IEEE Transactions on Information Theory, 56:2, 875-899, PMID: 20376281<\/li>\n\n\n\n<li>K. Oweiss, I. Badreldin (2015) \u201cNeuroplasticity subserving the operation of Brain Machine Interfaces,\u201d Journal of Neurobiology of Disease<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:29% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"563\" height=\"469\" src=\"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/OpticalClamp.png\" alt=\"\" class=\"wp-image-283 size-full\" srcset=\"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/OpticalClamp.png 563w, https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/OpticalClamp-300x250.png 300w\" sizes=\"auto, (max-width: 563px) 100vw, 563px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"has-text-align-center has-white-color has-dark-gray-background-color has-text-color has-background has-link-color has-large-font-size wp-elements-4f96740dea9e490ea54486a0639ffa9e\">Machine Learning and AI<\/p>\n<\/div><\/div>\n\n\n\n<p>We design and apply neural signal processing and feedback control algorithms for bi-directional neural interface systems, while embedding them into application-specific integrated circuits optimized for size, power consumption, and wireless operation for full implantation in the body. Our work also extends to developing agentic AI models inspired by principles of neuroplasticity and biological intelligence, bridging neuroscience with artificial intelligence to advance both clinical translation and machine learning theory. Some sample publications:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>K. Oweiss, Editor (2010), Statistical Signal Processing for Neuroscience and Neurotechnology, Academic Press, Elsevier, 1st edition, ISBN-13: 978-0-12-375027-3.<\/li>\n\n\n\n<li>S. Eldawlatly, Y. Zhou, R. Jin and K. Oweiss, (2010) \u201cOn The Use of Dynamic Bayesian Networks in Reconstructing Functional Neuronal Networks from Spike Train Ensembles\u201d, Journal of Neural Computation, MIT Press, 22:1, pp. 158-189, PMID: 19852619<\/li>\n\n\n\n<li>F. Zhang, M. Aghagolzadeh, and K. Oweiss, (2012) \u201cA Fully Implantable, Programmable and Multimodal Neuroprocessor for Wireless, Cortically Controlled Brain-Machine Interface Applications,\u201d Journal of Signal Processing Systems, pp. 1-11, doi:10.1007\/s11265-012-0670<\/li>\n\n\n\n<li>K. Oweiss, A. Mason, Y. Suhail, A. Kamboh, K. Thomson (2007) \u201cA Scalable Wavelet Transform VLSI Architecture for Real-Time Signal Processing in High Density Intra-cortical Implants,\u201d IEEE Transactions on Circuits and Systems, 54:6, pp. 1266-1278<\/li>\n<\/ul>\n\n\n\n<div class=\"wp-block-media-text is-stacked-on-mobile\" style=\"grid-template-columns:28% auto\"><figure class=\"wp-block-media-text__media\"><img loading=\"lazy\" decoding=\"async\" width=\"530\" height=\"599\" src=\"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/Lead-VTAs.jpg\" alt=\"\" class=\"wp-image-281 size-full\" srcset=\"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/Lead-VTAs.jpg 530w, https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-content\/uploads\/sites\/675\/2025\/09\/Lead-VTAs-265x300.jpg 265w\" sizes=\"auto, (max-width: 530px) 100vw, 530px\" \/><\/figure><div class=\"wp-block-media-text__content\">\n<p class=\"has-text-align-center has-white-color has-dark-gray-background-color has-text-color has-background has-link-color has-x-large-font-size wp-elements-5b113c5a0ebb12a9688546d9053cce33\">Translational Neuroscience<\/p>\n<\/div><\/div>\n\n\n\n<p>We develop computational models of basal ganglia circuits to elucidate mechanisms of Deep Brain Stimulation (DBS) and optimize its parameters for conditions such as Parkinson\u2019s disease, essential tremor, and sensory restoration. Our goal is to provide a systems-level understanding of DBS and develop feedback control techniques for closed-loop stimulation that minimize adverse effects of current open-loop approaches. Some sample publications:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>J. Liu, H. Khalil, K. Oweiss (2011) \u201cModel-based analysis and control of a network of Basal Ganglia spiking neurons in the normal and Parkinsonian states,\u201d Journal of Neural Engineering, 8: 045002 (16pp), PMID: 21775788<\/li>\n\n\n\n<li>J. Liu, H. Khalil, K. Oweiss (2011)\u201cNeural Feedback for Instantaneous Spatiotemporal Modulation of Afferent Pathways in Bi-directional Brain Machine Interfaces,\u201d IEEE Transactions on Neural Systems &amp; Rehabilitation Engineering, 19:5, pp 521-533, PMID: 21859634<\/li>\n\n\n\n<li>M. Grosse-Wentrup, D. Mattia, K. Oweiss (2011), \u201cUsing Brain-Computer Interfaces to Induce Neural Plasticity and Restore Function,\u201d Journal of Neural Engineering, 8: 025004, PMID: 21436534<\/li>\n\n\n\n<li>J. Daly, J. Liu, M. Aghagolzadeh, K. Oweiss (2012), \u201cOptimal Space Time Precoding of Artificial Sensory Feedback through Mutichannel Microstimulation in Bi-directional Brain Machine Interfaces \u201c J. of Neural Engineering, 9, 065004, doi:10.1088\/1741-2560\/9\/6\/065004<\/li>\n<\/ul>\n\n\n\n<p>A full list of publications is available here (<a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/?term=%28Oweiss+K%5BAuthor%5D%29+OR+Oweiss+KG%5BAuthor%5D\"><b>Pubmed<\/b><\/a>, <a href=\"https:\/\/scholar.google.com\/citations?user=IvzMgzQAAAAJ&amp;hl=en\"><b>Google Scholar<\/b><\/a>)<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u201cThere is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.\u201d Francis crik Basic Neuroscience My lab has a long-standing interest in investigating the neural mechanisms underlying sensorimotor integration, and the extent to which they can guide the engineering of clinically [&hellip;]<\/p>\n","protected":false},"author":1371,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/page-sidebar-none.php","meta":{"_acf_changed":false,"inline_featured_image":false,"featured_post":"","footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-27","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-json\/wp\/v2\/pages\/27","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-json\/wp\/v2\/users\/1371"}],"replies":[{"embeddable":true,"href":"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-json\/wp\/v2\/comments?post=27"}],"version-history":[{"count":0,"href":"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-json\/wp\/v2\/pages\/27\/revisions"}],"wp:attachment":[{"href":"https:\/\/faculty.eng.ufl.edu\/oweisslab\/wp-json\/wp\/v2\/media?parent=27"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}